DMSA Chelation

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DMSA is used to remove toxic heavy metals. It is particularly effective at removing lead and mercury. If you have lead poisoning symptoms or arsenic poisoning symptoms DMSA can help you. It is safe and works very quickly. No Prescription Needed.

Toxins May Be Making You Sick! The Urine Test shows the presence of 20 deadly toxic metals that might be in your body.

Urine Test for Detoxing


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DMSA For Detoxing Lead and Mercury

Our bodies are constantly exposed to an onslaught of environmental toxins. Lead and mercury are two heavy metals that seem to have found their way into almost everyone. Lead and mercury do not occur naturally in the body and as such are very toxic. These two heavy metals are known to interfere with how nerves communicate.

Meso-2,3-dimercaptosuccinic acid (DMSA) is a compound approved in the 1960’s by the FDA for the removal (chelation) of heavy metals. DMSA is considered the preferred agent for the chelation (removal) of heavy metals in both adults and children. Mercury is considered to be the second most toxin substance on the planet (uranium is #1) and the negative effects of mercury exposure are well documented. Meso-2,3-dimercaptosuccinic acid (DMSA) is also known as succimer and sold as a prescription under the trade name Chemet.

DMSA is also sold as an over the counter nutritional supplement in some areas but it is often very difficult to find and can be very expensive (over $1 per capsule). DMSA has a somewhat strong sulfur like smell. It’s chemical properties make it particularly suited to chelate (remove via excretion) mercury and lead, the two most common toxic heavy metals in people.

One of the main advantages of DMSA is its large therapeutic window. This means there is a wide margin between the amount necessary to produce the intended result and the level that could potentially overload the patient. This makes DMSA exceptionally safe.

How Did I Get Heavy Metals (Mercury and Lead) In My Body?

There are several possible ways heavy metals got into your body. Below each of the more common exposures will be discussed. Remember there are no safe levels for heavy metals. Chelation of toxic heavy metals with DMSA is well documented in the scientific literature. There are several other chelation agents but DMSA so far as been proven to be the safest and most effective.


There are 4 main sources of mercury poisoning:

  1. In Vitro, passed from mother to baby
  2. Vaccinations
  3. Dental Amalgams or ‘Silver Fillings’
  4. Contraception Pills and Contact Lense Solution

1. In Vitro

A mother with mercury in her body will pass it into her baby. The level of mercury in the tissue of the fetus, newborn, and young children is directly proportional to the number of silver fillings in the mother’s mouth.

2. Vaccinations

Vaccinations are the #1 mercury exposure in infants, and the #2 exposure in adults.

  • 25% of vaccines today still contain mercury.
  • Flu shots still contain mercury.
  • When mercury is removed from flu shots, it is replaced with other heavy metals such as aluminum and formaldehyde.

Mercury is used as a preservative in vaccinations. Vaccinations are currently a hot topic of debate with some parents linking autism to vaccinations. Flu shots contain mercury also, as a preservative. According to the EPA the average child can tolerate 0.3 micrograms of mercury. Note that a 2 month old infant receiving all 4 scheduled vaccinations (DtaP, Polio, Hib, Hepatitus B) will have a mercury level of 62.5 micrograms, 125 times higher than the EPA ‘safe’ level.

3. Dental Amalgams or ‘Silver Fillings’

Amalgam fillings leech methyl-mercury into your body. Methyl-mercury is particularly dangerous as its attracted to tissues and organs and can actually cross the blood brain barrier and get into your brain.

Fact: Most major countries other than the U.S. have extensive bans and health warnings regarding the use of amalgam fillings.
This includes Austria, Australia, Canada, France, Great Britain, Japan, New Zealand, Norway, Sweden, and Switzerland

Fact: In 1988 scrap dental amalgam material was declared a hazardous waste by the EPA (Environmental Protection Agency).
OSHA has certain mandates present to handle amalgam fillings before going into and out of your mouth.

The OSHA guidlines include:

  • Scrap amalgam must be stored in an unbreakable, tight sealed container away from heat.
  • Use a ‘no-touch’ technique for handling the amalgam
  • Store under liquid, preferably glycerin or photographic fixer solution

The video in the right column explains how mercury from dental fillings gets out of the filling and into your body: As the movie clearly shows, activities such as brushing your teeth and drinking hot liquids can increase your exposure to methyl-mercury (mercury vapor) from 10 to 100 times. What about fish?There is inorganic mercury in fish but the amount that actually ends up in the human body from fish consumption is very low and has been blown out of proportion by the media.

4. Contraception Pills and Contact Lense Solution

Mercury used to be used in both of these products. It has since been discontinued. Using these products in the 1980’s would have exposed you to mercury, which in turn would be passed from mother to child.


Lead is one of the most prominent metals you will see on any tests.

Our parents were part of the lead generation, it takes 4 generations to eliminate their exposures.

Sources include leaded paint, leaded gasoline, painted dishes, toys from China, candy from Mexico, children’s jewelry, and canned foods to name just a few.

The point is, if its in your body you need to get it out.

DMSA is able to effectively chelate lead from the human body. Lead is particularly toxic to children, leading to Attention Deficit Disorder (ADD) and Hyperactive Disorders. Their growing nervous system is negatively impacted by chronic and acute lead exposure.

DMSA has been shown to be safe for use in children. The 24 hour urine challenge should be done before and after a DMSA chelation program. During the Urine Challenge, DMSA is used as the provoking agent to measure the level of lead in the body.

DMSA Chelation

The chemical process behind how DMSA works to chelate heavy metals from the body is somewhat technical and beyond the scope of this article. The basic mechanism is that DMSA has receptor sites that the heavy metals bind to.

New research suggests the following action. Heavy metals reside inside the cells of the body and DMSA cannot enter the cells. Instead glutathione (the body’s natural chelator) residing inside the cell pushes the metals out of the cell whereby they are picked up by DMSA and excreted. Now you might say can’t I just take a glutathione supplement and force more heavy metals out of the cell? The answer is no because naturally occurring glutathione levels are 100 higher inside the cell than outside. Any glutathione supplement you take will end up circulation around the outside of the cell only.

What you need to do instead is take the precursor for glutathione so your body will manufacture its own glutathione.

One known pre-cursor (the chemical that allows your body to make its own glutathione) is N-AcetylCysteine, abbreviated as NAC. Great video here as a Medical Doctor explains how NAC works and why you should take it even if you are not detoxing.

Glycine also plays a large role in the production of glutathione, which is why its in the DMSA Synergy product.

Chelating agent is further explained. DMSA should be taken in on again and off again cycles. Ideally, 3 days on and 11 days off. The reason is that the body needs 11 days to regenerate its glutathione levels. Three days on and 11 days off is the fastest and safest way to use DMSA to chelate heavy metals.

DMSA and the Blood Brain Barrier

As previously stated DMSA can NOT cross the blood brain barrier. One study exists with lab rats wherein the DMSA did cross the blood brain barrier. However these test animals were so toxic that their normal functioning was greatly impaired.

The results of this test have never been duplicated so its safe to say that DMSA cannot cross the blood brain barrier.

DMSA must be taken in conjunction with alpha-lipoic acid to cross the blood brain barrier. After you have chelated the heavy metals from your body (know as ‘lowering your body burden’) you should then add alpha-lipoic acid with your DMSA to pull the mercury and other metals from your brain.

DMSA is taken in capsule form. Other competing forms of chelation, namely ETDA (suppositories) and DMPS (intraveniously) are more dangerous and less effective.

DMSA is thought to remove small amounts of beneficial minerals, therefore a vitamin and mineral supplement such as a high quality multi vitamin should be taken in conjunction with DMSA. Top of Page