Chelating Agent

Chelating agents are chemicals that can bond with some metals. In cases of heavy metal poisoning the chelating agent attaches itself to a foreign metal such as lead or mercury. Your body then excretes this chelating agent usually in the urine. Because the metal, in this example lead, is attached to the chelating agent your body also gets rid of the lead.

It is interesting to note that the chelating agent partially neutralizes targetted heavy metals. When the agent attaches itself to a toxic heavy metal like lead the lead is no longer able to interact with other beneficial elements in your body like calcium. This is how and why chelating agents are used to treat various poisonings such as lead poisoning and mercury poisoning.

The process of treating certain poisonings with a chelating agent is called ‘chelation therapy.’ The chemical used in this chelation therapy is called a chelating agent. The plural is chelating agents. A common chelating agent is dimercaprol or DMSA. Also called succimer, DMSA is a short form for the full chemical name, dimercaptosuccinic acid.

Chelation Pronunciation

Many people have not heard the word ‘chelation’ pronounced. Replace the ‘ch’ with a ‘k’ and you get the word ‘keylation’ which rhymes with ‘elation’ or ‘sedation’. Pronounced or say it like this: ‘KEY’ ‘LAY’ ‘SHUN’ – chelation.

Chelation and Chelating Agents

“Is the administration of chelating agents to remove heavy metals from the body. For the most common forms of heavy metal poisoning — those involving lead, arsenic or mercury — the standard of care in the USA dictates the use of dimercaptosuccinic acid (DMSA).”

Wikipedia (chelating agent)

The supplement or medicine that Dr. Cutler is describing is called a chelating agent. It is the actual chemical that binds to the toxic heavy metals, it is properly called a chelating agent. The reason it is called a chelating agent is that it leaves your body when it has done its job. Any good chelating agent will do this. In the case of DMSA most of it has left your body after 4 hours.

“Chelation is the process where you take a medicine (or supplement) that binds strongly to the toxic metal in question and is then excreted from the body while holding on to the metal and thus carries it out. DMSA is a chelating agent for lead, mercury, etc.

In a chemical sense, “chelation” refers to one molecule grabbing on to a metal atom with more than one attachment. Thus chelating agents are things that have more than one attaching group, like DMSA that has 2 sulfurs to attach to heavy metal atoms.”

Dr. Ancy Cutler

Why Use a Chelating Agent?

Heavy metals such as lead and mercury do NOT belong inside the human body. There are no safe levels for heavy metals. This is exactly why a proven chelating agent is vital to good health. Metals are actually commonly found in most people for a variety of reasons and are suspected to cause and worsen the following ailments:

  • Fibromyalgia
  • Autism
  • Alzheimer’s Disease
  • Inability to lose weight or keep weight off

These are just a few of the most common ailments heavy metals can cause.

Many people experience a variety of symptoms with no clear diagnoses of any particular condition and they may respond very well to chelation therapy. Such symptoms include, but are not limited to:

Brain Related SymptomsBody Related Symptoms
  • Depression
  • Anxiety
  • Dizziness
  • Irritability
  • Unexplained anger
  • Inability to concentrate
  • Ringing in the ears
  • Insomnia
  • Sensitivity to sound
  • Forgetfulness
  • Mild fatigue
  • Eye lid twitches
  • Face twitches
  • Digestive issue
  • Constipation
  • Diarrhea
  • Frequent bad breath
  • Constant body odor
  • Abnormal menses
  • Low body temperature
  • Cold hands and feet
  • Tender teeth
  • Metal taste in mouth
  • Nail fungus


If you search the internet you will soon find that many individuals report a lessening of of the symptoms of their condition after chelation. Below are just a few of the more common medical conditions associated with heavy metal poisoning, chelation therapy is thought to help with all of these.

Parents report that their autistic children show great improvements while chelating with DMSA (the preferred chelating agent) and following a good chelation therapy schedule. They listen better, can focus better, speech improves, and self stimming decreases. Removing the metals in their bodys allows them to move towards being the child they should be.

Parents of autistic children should visit this page for more information, learn how to use a proper chelating agent like DMSA and figure out how much to give your child. Particularly interesting is what the DAN (Defeat Autism Now) doctors have to say about DMSA chelation therapy.


Fibromyalgia patients report a noticable decrease in pain and an increase in mobility. The annoying fatigue is lessened or disappears completely following chelation therapy. Sleep improves greatly, increasing the sense of well-being. Bowel function and bladder problems improve. This may be due to how DMSA chelation therapy reduces levels of silicon in blood and tissue thereby reducing blood pressure, improving kidney function, preventing or retarding the progression of chronic renal failure. Basically DMSA allows your body to function better by removing metals (chelation) that were blocking its internal healing mechanisms and allows the body to heal itself.

Alzheimer’s Disease

The symptoms of alzheimer’s are well documented. This is a very difficult disease to live with, both for the victim and the caregiver/partner/spouse. Even a mild improvement in the symptoms associated with Alzheimer’s Disease will improve the quality of life for all concerned. If you haven’t tried DMSA chelation therapy yet a one month trial might be just the thing. You may be asking yourself, “Why didn’t I try this sooner?”

Inability To Lose Weight

Some people are unable to lose weight and they don’t know why. This is often due to burned out Leptin receptors in your brain. Fat does not make you fat, it’s your bodies inability to burn fat that makes it impossible to lose weight in mercury poisoned individuals. Leptin is the hormone that tells your brain to burn fat for energy. If the Leptin receptors in your brain can’t ‘hear’ Leptin your body will NOT burn fat for energy. Instead your body will store fat, making it impossible to lose weight. Removing mercury from your brain with a chelating agent will allow the Leptin receptors to heal. Once they are healed they will listen to Leptins message to burn fat instead of store it. As a side note, your body can only use two things for energy, fat and sugar. So if your body is unable to burn fat for energy it is forced to burn sugar. This explains cravings for sugar. Keep in mind ‘sugar’ includes all things that the body turns into sugar, such as bread, pasta, potatoes etc. Healing your Leptin receptors and cutting out foods that your body turns into sugar will force your body to burn fat for energy and you will rapidly lose weight. Using a proper chelating agent like DMSA

How Much DMSA Do I Take?

How much DMSA you take is based solely on body weight. Dosage with this powerful chelating agent for chelation therapy is given in ranges so you can start at a lower level and work your way up to the higher level once your body gets used to DMSA The exact formula for chelation therapy and recommendations is provided when you order DMSA.

What To Expect

Initially you may feel slightly tired when taking DMSA. However, once the metals start leaving your body you will experience a sense of well-being and increased energy and focus. Your ability to concentrate will increase greatly. The so-called ‘brain fog’ will be gone. Your memory will improve. In general you will feel sharper.

Where To Buy DMSA

Prescription DMSA (chelating agent) costs approximately $2-$3 per capsule and many over the counter manufacturers have stopped supplying DMSA completely as the US government is trying to make DMSA prescription only. This will put it out of the reach of many people.

A source of inexpensive, high-quality DMSA is still available. It is made in a FDA approved pharmaceutical facility. It’s available without a prescription in a variety of sizes. Click here to buy DMSA.

200 DMSA Capsules
High Quality DMSA

Chelate Effect

The chemical interaction and bonding properties that chelation agents like DMSA have can vary in strength. This variation in strength is the chelate effect. Different agents have different strenghts. For example DMSA bonds strongly to lead and mercury. It bonds less strongly to gadolinium (used in MRI contrast agents).

It is still effective at chelating gadolinium. Try to picture a magnetic attraction. Dimercaprol still ‘attracts’ gadolinium, just not as strongly as it attracts some other elemental metals.

Chelating agents are more stable than compounds that are not chelated. Chelates are complex chemical compounds with a ring structure surrounding an atom. There are various points of attachment on this ring.

More attachments points means it attaches more strongly to similar metal ions on other chemical compounds. This is known as the ‘chelating effect.’

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